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What does the treatment involve?

Fibrin membrane is a platelet-rich plasma preparation, also known as PRF, which gives extra value to recovery from any eye surgery, as it accelerates and improves the tissue cicatrisation process. 

When is this treatment indicated?

We use fibrin membrane in eyelid, lacrimal and eye orbit surgery for different pathologies, reconstructions or purely aesthetic operations, such as a blepharoplasty.

How is it performed?

We produce it in the laboratory at the Centre using the patient's own blood. This ensures that we comply with all the protocols and that the membrane is produced in optimum conditions so that it is viable, the platelets do not break and detach from the growth factors. In this way, an hour and a half before operating, we already have the fibrin membrane propeared so that it is in the best conditions at the time of the operation. 

When we are halfway through surgery, we take out the membrane and apply it before suturing, so that it stays inside, and after too, on top of the sutures. Once the operation is complete, the platelet growth factors will spread throughout the whole area for an extra supply that the blood would take much longer to generate. After a four or five days, when all the components have played their part, the membrane will dissolve. 


First, we have managed to reduce the postoperative period like never seen before in our specialism: quicker cicatrisation and less haematoma, oedema and swelling. However, in addition, this preparation provides the patient with multiple benefits. It is an autologous and biocompatible procedure that the patient does not reject because it is produced using their own blood, so it can be performed on anyone of any age, even if they are undergoing medical treatment. It is a completely painless procedure, because the only thing we need from the patient is their blood, which we draw for the preoperative blood test anyway. In addition, the application of fibrin membrane does not extend the duration of the surgery.  

Possible risks

This treatment is contraindicated in the case of eye pathologie related to a microbial infection (bacteria, virus, fungus...). In the event that the patient has an infectious disease they should inform the healthcare professional before their blood is drawn, so that suitable precautionary measures can be taken. 

Professionals who perform this treatment

Frequently asked questions

  • Depende de cada paciente pero, en general, la cicatrización suele ser al cabo de los tres meses en pacientes normales y, en cambio, los pacientes a los que les hemos aplicado la membrana ya muestran un aspecto mucho mejor al mes y medio. Además, a los diez días ya hay menos hematoma e hinchazón. Todas estas evidencias las hemos recogido en un estudio que hemos elaborado en el Centro con cien ojos y las hemos objetivado con fotografías.

  • Pusimos en marcha este procedimiento y comenzamos a trabajar con la membrana de fibrina en el año 2018, ya que hasta ese momento no se había llevado a la cirugía plástica ocular. La podemos aplicar en cualquier operación de nuestra especialidad: en blefaroplastias, donde eliminamos párpados caídos y bolsas en los ojos, en reconstrucciones de pacientes que han perdido un ojo y les colocamos un implante, en intervenciones del lagrimal en las que necesitamos que la cicatrización sea muy rápida para evitar infecciones…